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Are we investing wisely? A systematic analysis of nationally funded antimicrobial resistance projects in Republic of Korea, 2003–2013

机译:我们是否明智地投资?对大韩民国2003 - 2013年国家资助的抗菌药物耐药项目进行系统分析

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摘要

From 2003–2013, South Korea has conducted the National Antimicrobial Resistance Safety Control Program (NARSCP). The purpose of the current study was to systematically review national antimicrobial resistance (AMR) research trends and to provide guidance on future allocation of research funding to enable a comprehensive approach in AMR control. This study collected project reports related to AMR published by the Ministry of Food and Drug Safety, the Ministry of Health and Welfare and the Korea Centers for Disease Control and Prevention between 2003 and 2013. These reports were analysed by topics based on the AMR action plan of the World Health Organization (WHO), period of study, categories along the research pipeline and types of receiving institution. A total of 198 project reports were included, with total funding of US$18.3 million. Mean funding per award was US$92 750, with a median of US$71 714. Among the WHO-suggested criteria, the basic microbial research and surveillance sector accounts for 143 (72.2%) of all awards. Yearly project funding increased from US$961 476 in 2003 to US$1 553 294 in 2013. Operational research was 61.5% and product development was 0.7% of the basic microbial research and surveillance sector. By institution, academia received 145 awards (73.2%). During progress of the NARSCP, total research funding increased significantly, but most awards were focused on understanding the overall picture of the nationwide AMR status. More balanced funding is needed, and encouraging active participation of private and international sectors is also required in reducing AMR.
机译:从2003年至2013年,韩国实施了国家抗菌素耐药性安全控制计划(NARSCP)。本研究的目的是系统地审查国家抗微生物药物耐药性(AMR)的研究趋势,并为未来研究资金分配提供指导,以实现一种全面的AMR控制方法。这项研究收集了2003年至2013年间由食品和药品安全部,卫生和福利部以及韩国疾病控制与预防中心发布的与AMR相关的项目报告。这些报告是根据AMR行动计划进行主题分析的世界卫生组织(WHO)的研究,研究期限,研究过程中的类别以及接收机构的类型。总共包括198个项目报告,总资金为1830万美元。每个奖项的平均资金为92 750美元,中位数为71 714美元。在世界卫生组织建议的标准中,基础微生物研究和监测部门占所有奖项的143个(72.2%)。每年的项目资金从2003年的961 476美元增加到2013年的1 553 294美元。运营研究占基础微生物研究和监测部门的61.5%,产品开发占0.7%。按机构划分,学术界获得145个奖项(占73.2%)。在NARSCP的进展期间,研究经费总额显着增加,但是大多数奖项的重点是了解全国AMR状况的总体情况。需要更加平衡的资金,并且还需要鼓励私营和国际部门积极参与以减少AMR。

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